Both Aa and tau pathology appear to be associated with default mode network integrity before clinical onset of Alzheimer disease (AD).
This is according to a study by Liang Wang, M.D., and colleagues at Washington University in St. Louis, Missouri.
Accumulation of Aa and tau proteins, the pathologic hallmarks of AD, starts years before clinical onset. Pathophysiological abnormalities in the preclinical phase of AD may be detected using cerebrospinal fluid (CSF) or neuroimaging biomarkers, according to the study background....
Both Aa and tau pathology appear to be associated with default mode network integrity before clinical onset of Alzheimer disease (AD).
This is according to a study by Liang Wang, M.D., and colleagues at Washington University in St. Louis, Missouri.
Accumulation of Aa and tau proteins, the pathologic hallmarks of AD, starts years before clinical onset. Pathophysiological abnormalities in the preclinical phase of AD may be detected using cerebrospinal fluid (CSF) or neuroimaging biomarkers, according to the study background....