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Idiopathic Scoliosis Linked to Disruptions in Cerebrospinal Fluid Flow

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Idiopathic scoliosis refers to an abnormal lateral curvature of the spine. It has no known cause and affects roughly three out of every 100 adolescents. A new study in zebrafish suggests that irregular fluid flow through the spinal column brought on by gene mutations is linked to a type of scoliosis that can affect humans during adolescence. Found in humans and zebrafish, these mutated genes damage the cilia - tiny hair-like projections that line the spinal canal and help move the fluid - and lead to a curvature of the spine....

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