Mice lacking the protein Alix develop hydrocephalus or "water on the brain", report a team led by researchers at St. Jude Children's Research Hospital.
Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier. The research appears online in the scientific journal emNature Communications/em.
"We have successfully developed the first mouse model for Alix that allows us to study the consequences of Alix loss of function in vivo....
Mice lacking the protein Alix develop hydrocephalus or "water on the brain", report a team led by researchers at St. Jude Children's Research Hospital.
Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier. The research appears online in the scientific journal emNature Communications/em.
"We have successfully developed the first mouse model for Alix that allows us to study the consequences of Alix loss of function in vivo....